Biosynthetic osteogenic proteins and osteogenic devices...

C - Chemistry – Metallurgy – 12 – N

Patent

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530/13, 167/327,

C12N 15/18 (2006.01) A61K 38/17 (2006.01) A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 27/36 (2006.01) A61L 27/56 (2006.01) C07K 14/51 (2006.01) C07K 16/22 (2006.01) A61C 8/00 (2006.01) A61F 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1338663

Disclosed are 1) osteogenic devices comprising a matris containing osteogenic protein and methods of inducing endochondral bone growth and cartilage in mammals using the devices; 2) amino acid sequence data, amino acid composition, solubility properties, structural features, homologies and various other data characterizing osteogenic proteins, 3) methods of producing osteogenic proteins using recombinant DNA technology, and 4) osteogenically and chondrogenically active synthetic protein constructs.

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