Biotin-derivatives and their conjugates with chelating agents

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/4188 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2436242

Formula (I) compounds are described where the groups are as defined here below, processes for their preparation, and their uses for the preparation of conjugates with radionuclides for use in human and animal therapy and diagnostics, particularly for the diagnosis and therapy of pathological conditions such as tumours.

L'invention concerne des composés représentés par la formule (I) dans laquelle les groupes sont tels que définis plus bas, leurs procédés de préparation, et leurs utilisations dans la préparation de conjugués avec des radionucléides destinés à être utilisés dans des méthodes thérapeutiques et diagnostiques chez les humains et les animaux, en particulier dans le diagnostic et la thérapie d'états pathologiques tels que les tumeurs.

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