Biotin diaminoderivatives and their conjugates with...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2621960

Formula (I) compounds are described: Formula (I) where the radicals are as defined in the description, processes for their preparation, and their uses for the preparation of conjugates with radionuclides for use in human and animal therapy and diagnostics, particularly for the diagnosis and therapy of pathological conditions such as tumours.

La présente invention porte sur des composés de Formule (I) : Formule (I) où les radicaux sont tels que définis dans la description, sur des procédés de synthèse desdits composés, et sur leurs applications dans la formation de conjugués avec des radionucléides pouvant être employés en thérapie et en diagnostic humains et animaux, en particulier pour le diagnostic et la thérapie d'états pathologiques tels que des tumeurs.

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