Biphasic multilamellar lipid vesicles

Details Biphasic multilamellar lipid vesicles Biphasic multilamellar lipid vesicles

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 8/14 (2006.01) A61K 38/21 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01)

Patent

CA 2168260

A biphasic multilamellar lipid vesicle comprising a plurality of spaced apart lipid bilayers that include a liposome-forming component and optionally a biologically active agent entrapped within the lipid bilayers. The lipid vesicle also comprises peripheral aqueous solution compartments formed between the lipid bilayers and a central lipophilic core compartment substantially at the center of the multilamellar lipid vesicle.

Vésicule lipidique multilamellaire biphasique comportant une pluralité de doubles couches lipidiques espacées les unes des autres et dotées d'un constituant de formation de liposomes et éventuellement d'un agent à activité biologique enfermé dans les doubles couches lipidiques. La vésicule lipidique comporte également des cavités périphériques remplies d'une solution aqueuse et formées entre les doubles couches lipidiques et une cavité centrale lipophile située sensiblement au centre de la vésicule lipidique multilamellaire.

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