Biphenyl hydroxamic acids

Details Biphenyl hydroxamic acids Biphenyl hydroxamic acids

C - Chemistry, Metallurgy

07

C

167/246, 260/452

C07C 271/10 (2006.01) A61K 31/17 (2006.01) C07C 275/64 (2006.01)

Patent

CA 1292005

Abstract BIPHENYL HYDROXAMIC ACIDS Biphenyl hydroxamic acids are provided having the structure Image wherein m is 1 to 7, X is S, O or NH, R is H, lower alkyl, aryl, aralkyl or cycloalkyl and R1 is H, lower alkyl, aryl, aralkyl, cycloalkyl, alkanoyl or aroyl. These compounds are inhibitors of .DELTA.5-lipoxy- genase and as such are useful as antiallergy agents.

538041

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