Biphenyl substituted spirotetronic acids and their use for...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 307/94 (2006.01) A61K 31/343 (2006.01) A61K 31/4353 (2006.01) A61P 31/12 (2006.01) C07D 405/12 (2006.01) C07D 491/10 (2006.01) C07D 493/10 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2660084

The present invention relates to novel substituted spirotetronic acids (I) in which R1 and R2, together with the carbon atom to which they are bonded, form a group of the formula (1), (2), (3) or (4), where * is the carbon atom to which R1 and R2 are bonded, to processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular of retroviral disorders, in people and/or animals.

La présente invention concerne de nouveaux acides spirotétroniques substitués de formule (I) dans laquelle R1 et R2 forment ensemble avec l'atome de carbone auquel ils sont rattachés un groupe de la formule (1), (2), (3) ou (4), * désignant l'atome de carbone auquel R1 et R2 sont rattachés; des procédés pour les préparer; leur utilisation pour le traitement et/ou la prophylaxie de maladies ainsi que leur utilisation dans la préparation de médicaments destinés au traitement et/ou à la prophylaxie de maladies, en particulier de maladies rétrovirales, chez l'homme et/ou l'animal.

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