C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/92 (2006.01) A61K 31/67 (2006.01) A61P 9/10 (2006.01) C07C 237/42 (2006.01) C07C 311/21 (2006.01) C07D 213/56 (2006.01) C07D 213/81 (2006.01) C07D 215/06 (2006.01) C07D 231/12 (2006.01) C07D 295/135 (2006.01) C07D 295/192 (2006.01) C07D 295/215 (2006.01)
Patent
CA 2412116
The invention relates to substituted piperazine derivatives of general formula (I), wherein R1 to R7 have the meanings given in claim no. 1, isomers thereof and salts thereof, especially physiologically compatible salts thereof, which represent valuable inhibitors of the microsomal triglyceride transfer protein (MTP). The invention also relates to medicaments containing these compounds and to the use and production of the same.
La présente invention concerne des dérivés de pipérazine substitués de formule générale (I) dans laquelle R?1¿ à R?7¿ sont tels que définis dans la revendication 1, leurs isomères et leurs sels, notamment leurs sels acceptables d'un point de vue physiologique, qui sont de bons inhibiteurs de la protéine microsomale de transfert de triglycéride (MTP). Cette invention concerne également des produits pharmaceutiques contenant ces composés, et leur utilisation ainsi que leur préparation.
Dahmann Georg
Hauel Norbert
Mark Michael
Priepke Henning
Thomas Leo
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
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