C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/34 (2006.01) A61K 8/49 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61P 17/00 (2006.01) A61Q 19/00 (2006.01) C07C 233/87 (2006.01) C07C 235/66 (2006.01) C07C 235/78 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2468796
The invention concerns bi-aromatic compounds of general formula (I), wherein: R¿1? is (a) or (b), R¿5? being hydroxy or alkoxy and R¿6? being alkyl, OR¿14? or SR¿14? which are PPAR-gamma receptors. They are useful in pharmaceutical compositions for use in human and veterinary medicine (in dermatology, as well as for cardiovascular diseases, immune diseases and/or diseases related to lipid metabolism), or in cosmetic compositions.
Les composés de formule (I) : dans laquelle R1 est (a) ou (b) R5 étant hydroxy ou alkoxy et R6 étant alkyle OR14 ou SR 14, sont des activateurs des recepteurs de type Peroxisome Proliferator-Activated Receptor de sous -type Y (PPARY). Ils sont utiles dans des compositions pharmaceutiques destinées à un usage en médecine humaine ou vétérinaire (en dermatologie, ainsi que dans le domaine des maladies cardio-vasculaires, des maladies immunitaires et/ou des maladies liées au métabolisme des lipides), ou bien encore dans des compositions cosmétiques.
Bernardon Jean-Michel
Clary Laurence
Terranova Eric
Galderma Research & Development
Galderma Research & Development S.n.c.
Robic
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