C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 311/16 (2006.01) A01N 1/02 (2006.01) A61K 31/275 (2006.01) A61K 31/33 (2006.01) C07C 311/29 (2006.01) C07C 311/41 (2006.01) C07C 317/14 (2006.01) C07C 323/67 (2006.01) C07C 381/00 (2006.01)
Patent
CA 2247749
Compounds of the formula I Image in which the symbols have the meanings indicated in the claims, have outstanding antiarrhythmic properties. They exhibit a cardioprotective component. They can inhibit or greatly decrease, in a preventive manner, the pathophysiological processes in the formation of ischemically induced damage, in particular in the elicitation of ischemically induced cardiac arrhythmias. Moreover, they have a strong inhibitory action on the proliferation of cells.
Les composés de formule I Image , dans laquelle les symboles ont la signification indiquée dans les revendications, ont des propriétés anti-arythmisantes remarquables. Ils présentent une composante cardioprotectrice. Ils peuvent inhiber ou considérablement réduire, de façon préventive, les processus pathophysiologiques dans la formation des dommages causés par l'ischémie, en particulier dans l'élicitation d'arythmie cardiaque induite par l'ischémie. De plus, ils exercent une forte action inhibitrice sur la prolifération des cellules.
Faber Sabine
Jansen Hans-Willi
Kleemann Heinz-Werner
Lang Hans Jochen
Schwark Jan-Robert
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Hoechst Marion Roussel Deutschland Gmbh
Sanofi-Aventis Deutschland Gmbh
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