C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/5355 (2006.01) A61K 31/541 (2006.01) A61K 31/549 (2006.01) A61P 3/10 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2672307
Bipiperidinyl compounds of the formula I, are disclosed as useful for treating or preventing type 2 diabetes and similar conditions. Pharmaceutically acceptable salts and solvates are included as well. The compounds are useful as agonists of the g-protein coupled receptor GPR-119.
L'invention concerne des composés de bipipéridinyle de formule I qui sont utiles pour traiter ou prévenir les diabètes de type 2 et des états similaires. L'invention concerne également des sels et des solvats pharmaceutiquement acceptables. Les composés sont utiles en tant qu'agonistes du récepteur GPR 119 couplé à la protéine G.
Adams Alan D.
Freeman Stanley
Huang Yong
Santini Conrad
Szewczyk Jason W.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
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