C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/82 (2006.01) A61K 31/4427 (2006.01) A61K 31/444 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2679817
The present invention is directed to bipyridyl carboxamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
La présente invention concerne des composés bipyridylcarboxamide, qui sont antagonistes des récepteurs de l'orexine, et qui sont utiles dans le traitement ou la prévention de désordres et de maladies neurologiques et psychiatriques, dans lesquels les récepteurs de l'orexine sont impliqués. L'invention concerne également des compositions pharmaceutiques comprenant ces composés et l'utilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies, dans lesquelles les récepteurs de l'orexine sont impliqués.
Coleman Paul J.
Mercer Swati P.
Roecker Anthony J.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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