Bis-(2-haloethyl)aminophenyl substituted distamycin...

Details Bis-(2-haloethyl)aminophenyl substituted distamycin... Bis-(2-haloethyl)aminophenyl substituted distamycin...

C - Chemistry, Metallurgy

07

D

C07D 207/34 (2006.01) A61K 31/40 (2006.01)

Patent

CA 2199635

Novel antitumor and antiviral agents of formula (I) wherein n is 2, 3 or 4; one of R and R1 is hydrogen, C1-C4 alkyl, CF3 or C1-C4 alkoxy and the other is independently CF3, C1-C4 alkyl or C1-C4 alkoxy; and X is halogen; and the salts thereof are disclosed.

L'invention a pour objet de nouveaux agents antiviraux et antitumoraux présentant la formule (I), dans laquelle n est égal à 2, 3 ou 4; un élément parmi R et R¿1? est hydrogène, alkyle C¿1?-C¿4? CF¿3? ou alcoxy C¿1?-C¿4? et l'autre est, indépendamment, du CF¿3?, alkyle C¿1?-C¿4?, ou alcoxy C¿1?-C¿4?; et X est halogène. L'invention traite aussi des sels de ces agents.

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