C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 279/26 (2006.01) A61L 12/14 (2006.01) C08G 73/00 (2006.01)
Patent
CA 2352076
Bis-amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of bis-amido polybiguanides is also disclosed. The bis-amido polybiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic and otic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting/cleaning contact lenses.
L'invention concerne des polybiguanides bis-amido et leur utilisation en tant qu'agents antimicrobiens dans des compositions pharmaceutiques. Un procédé de synthèse de polybiguanides bis-amido est également décrit. Ces polybiguanides bis-amido sont utiles pour conserver des compositions pharmaceutiques, et plus particulièrement des compositions ophtalmiques et des compositions pharmaceutiques pour les oreilles ainsi que des compositions servant à traiter les lentilles de contact. Lesdits composés sont particulièrement utiles pour désinfecter/nettoyer les lentilles de contact.
Mcqueen Nathaniel D.
Park Joonsup
Alcon Laboratories Inc.
Smart & Biggar
LandOfFree
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