C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/50 (2006.01) A61K 31/4406 (2006.01) A61P 11/00 (2006.01) A61P 29/00 (2006.01) C07C 233/87 (2006.01) C07C 237/40 (2006.01) C07C 317/14 (2006.01) C07D 213/65 (2006.01) C07D 213/74 (2006.01) C07D 317/46 (2006.01) C07D 335/02 (2006.01) C07D 401/10 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2754946
There is provided compounds of formula (I), wherein Y, ring A, D1, D2a, D2b, D3, L1, Y1, L3 and y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.
L'invention porte sur des composés de formule (I), dans laquelle Y, le noyau A1, D1, D2a, D2b, D3, L1, Y1, L3 et Y3 ont les significations données dans la description, et sur leurs sels pharmaceutiquement acceptables, lesquels composés sont utiles dans le traitement de maladies dans lesquelles l'inhibition de la leucotriène C4 synthase est souhaitée et/ou requise, et en particulier dans le traitement d'un trouble respiratoire et/ou d'une inflammation.
Katkevics Martins
Nilsson Peter
Pelcman Benjamin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biolipox Ab
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