Bis-aryl amide and urea antagonists of platelet activating...

C - Chemistry – Metallurgy – 07 – D

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C07D 277/30 (2006.01) A61K 31/41 (2006.01) A61K 31/435 (2006.01) C07D 213/20 (2006.01) C07D 213/56 (2006.01) C07D 215/16 (2006.01) C07D 217/16 (2006.01) C07D 233/61 (2006.01) C07D 277/22 (2006.01) C07D 277/28 (2006.01) C07D 471/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2041687

31,249-00 Title: BIS-ARYL AMIDE AND UREA ANTAGONISTS OF PLATELET ACTIVATING FACTOR ABSTRACT OF THE INVENTION Bis-aryl amide and urea compounds of the general formula: Image wherein X is a divalent amide or urea substituent and Y is a nitrogen containing heterocycle, which compounds are inhibitors of platelet activating factor. Pharmaceutical compositions containing the compounds and methods of treating platelet activating factor associated conditions are also included.

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