Bis-aryl amide derivatives and methods of use

Details Bis-aryl amide derivatives and methods of use Bis-aryl amide derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 231/56 (2006.01) A61K 31/416 (2006.01) A61K 31/4725 (2006.01) A61K 31/5025 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2673652

Selected compounds are effective for prophylaxis and treatment of diseases, such as c Met mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

La présente invention concerne des composés choisis efficaces pour la prophylaxie et le traitement de maladies telles que des maladies induites par c Met. L'invention concerne des composés, des analogues et des promédicaments innovants et les sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques et des procédés de prophylaxie et de traitement de maladies et d'autres maladies ou affections notamment le cancer et des maladies similaires. La présente invention concerne également des procédés de fabrication de tels composés ainsi que des intermédiaires utilisables dans de tels procédés.

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