Bis-aryl kinase inhibitors and their use in the treatment of...

Details Bis-aryl kinase inhibitors and their use in the treatment of... Bis-aryl kinase inhibitors and their use in the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/381 (2006.01) A61K 31/4035 (2006.01) A61K 31/416 (2006.01) A61K 31/4725 (2006.01) A61P 35/00 (2006.01) C07D 215/04 (2006.01) C07D 215/20 (2006.01) C07D 333/38 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2611688

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Selon l'invention, des composés sélectionnés sont efficaces dans la prophylaxie et le traitement de maladies, telles que des maladies à médiation HGF. Cette invention a aussi pour objet de nouveaux composés, analogues, promédicaments et sels correspondants acceptables pharmaceutiquement, des compositions pharmaceutiques et des méthodes de prophylaxie et de traitement de maladies ou d'autres troubles engendrant un cancer et similaire. Ladite invention a, également, trait à des processus de fabrication de tels composés, ainsi que d'intermédiaires utilisés dans ces processus.

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