Bis(aryloxy)alkanes as inhibitors of the phospholipase a2...

C - Chemistry – Metallurgy – 07 – C

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C07C 323/52 (2006.01) A61K 31/19 (2006.01) A61K 31/22 (2006.01) C07C 59/90 (2006.01) C07C 317/44 (2006.01) C07C 323/53 (2006.01)

Patent

CA 2153739

Compounds having the formula I: Image I are inhibitors of the PLA2s enzymes. These compounds are useful as anti-allergic, anti-asthmatic, they are also useful in treating various inflammatory diseases such as rheumatoid arthritis, osteoarthritis, bursitis, psoriasis; immunoinflammatory disorders such as contact dermatitis, irritable bowel disease and the like.

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