Bis-benzo or benzopyrido cyclo hepta piperidene,...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/14 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) C07D 213/89 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/14 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/044 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2085878

Bis-benzo or benzopyrido piperidene, piperidylidene and piperazine compounds of formula (I), and pharmaceutically acceptable salts thereof are disclosed, wherein Z represents -(C(Ra)2)m-Y- (C(Ra)2n- or (.alpha.). The compounds of formula (I) possess anti-allergic and anti-inflammatory activity. Methods for preparing and using the compounds are also described.

Composés de dibenzo ou benzopyridopipéridène, pipéridylidène et pipérazine de la formule (I), et sels pharmaceutiquement acceptables de ces composés. Dans la formule (I), Z représente -(C(Ra)2)m-Y-(C(Ra)2)n- ou (alpha). Les composés de la formule (I) possèdent une activité antiallergique et anti-inflammatoire. On décrit aussi des procédés pour la préparation et l'utilisation de ces composés.

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