Bis(cyclopropanecarboxamido) alkadienedioic acids as renal...

Details Bis(cyclopropanecarboxamido) alkadienedioic acids as renal... Bis(cyclopropanecarboxamido) alkadienedioic acids as renal...

C - Chemistry, Metallurgy

07

C

167/187, 260/518

C07C 233/63 (2006.01) A61K 31/195 (2006.01) A61K 31/40 (2006.01) C07C 233/12 (2006.01)

Patent

CA 1297128

TITLE OF THE INVENTION BIS(CYCLOPROPANECARBOXAMIDO)ALKADIENEDIOIC ACIDS AS RENAL DIPEPTIDASE INHIBITORS ABSTRACT OF THE INVENTION Novel chemical compounds are provided which selectively inhibit the metabolism of renal dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are (Z,Z)-.alpha.,.alpha.'-bis(2,2-disubstituted cyclopropanecarboxamido)-.alpha.,.alpha.'-alkadienedioic acids.

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