Bis-dioxopiperazine derivatives and process for preparation...

Details Bis-dioxopiperazine derivatives and process for preparation... Bis-dioxopiperazine derivatives and process for preparation...

C - Chemistry, Metallurgy

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C07D 403/14 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 403/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1279642

ABSTRACT OF THE DISCLOSURE Disclosed are bis-dioxopiperazine derivatives and process for preparation thereof. The bis-dioxopiperazine derivatives are represented by the following formula (I): Image (I) wherein R1 represents an alkyl group having 1 to 6 carbon atoms; A represents an oxygen atom, a sulfur atom or a group of Image or Image wherein R2 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms or phenyl; R3 represents an alkyl group having 1 to 6 carbon atoms, phenyl or benzyl; and X and Y, which are respectively independent and are the same or different, represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms. The compounds(I) have antitumor activity.

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