Bis-esters of 1,1-alkanediols with 6-.beta.-...

Details Bis-esters of 1,1-alkanediols with 6-.beta.-... Bis-esters of 1,1-alkanediols with 6-.beta.-...

C - Chemistry, Metallurgy

07

D

260/110

C07D 499/00 (2006.01)

Patent

CA 1201709

Bis-Esters of 1,1-Alkanediols with 6-Beta-Hydroxymethylpenicillanic Acid 1,1-Dioxide and beta-Lactam Antibiotics Abstract Bis-Esters of 1,1-alkanediols with 6-beta(hydroxy- methyl)penicillanic acid 1,1-dioxide and 6-betaacyl- aminopenicillanic acids are useful as antibacterial agents. Intermediates useful for the preparation of these compounds include halomethyl, alkylsulfonyloxy- methyl and arylsulfonyloxymethylesters of 6-beta- (hydroxymethyl)penicillanic acid 1,1-dioxide and 6- beta-aminopenicillanoyloxymethyl-6'-beta-(hydroxymethyl)- penicillanate 1,1-dioxide.

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