Bis-isoquinolinium salts as long duration neuromuscular...

Details Bis-isoquinolinium salts as long duration neuromuscular... Bis-isoquinolinium salts as long duration neuromuscular...

C - Chemistry, Metallurgy

07

D

260/277.3

C07D 217/10 (2006.01) C07D 217/20 (2006.01)

Patent

CA 1178275

B340 Canada Abstract This invention relates to long duration neuromuscular blocking agents, known examples of which agents have been found to have cardiovascular and other side effects, and seeks to overcome the shortcomings of presently used agents. The compounds of this invention are trans, trans-2,21-(dimethylenebis (carbonyloxy-trimethylene))bis(1,2,3,4-tetrahydro-6,7,8-trimethoxy -2-alkyl-1 -(3,4,5-trimethoxybenzyl)isoquinolinium salts. The preferred compound has the following structure: Image AGS/JAH/7th December,1981.

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