C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/20 (2006.01) A61K 31/085 (2006.01) A61K 31/33 (2006.01) A61K 31/4375 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/498 (2006.01) A61K 31/517 (2006.01) C07C 43/205 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07D 213/30 (2006.01) C07D 213/64 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01) C07D 215/233 (2006.01) C07D 215/50 (2006.01) C07D 239/88 (2006.01) C07D 239/91 (2006.01) C07D 239/93 (2006.01) C07D 239/94 (2006.01) C07D 241/42 (2006.01) C07D 241/52 (2006.01) C07D
Patent
CA 2102780
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
Maguire Martin P.
Myers Michael R.
Persons Paul E.
Spada Alfred P.
Aventis Holdings Inc.
Goudreau Gage Dubuc
Rhone-Poulenc Rorer International (holdings) Inc.
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