Bis mono-and bicyclic aryl and heteroaryl compounds which...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/20 (2006.01) A61K 31/085 (2006.01) A61K 31/33 (2006.01) A61K 31/4375 (2006.01) A61K 31/4709 (2006.01) A61K 31/4725 (2006.01) A61K 31/498 (2006.01) A61K 31/517 (2006.01) C07C 43/205 (2006.01) C07C 43/225 (2006.01) C07C 43/23 (2006.01) C07D 213/30 (2006.01) C07D 213/64 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01) C07D 215/233 (2006.01) C07D 215/50 (2006.01) C07D 239/88 (2006.01) C07D 239/91 (2006.01) C07D 239/93 (2006.01) C07D 239/94 (2006.01) C07D 241/42 (2006.01) C07D 241/52 (2006.01) C07D

Patent

CA 2102780

This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.

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