Bis-naphthalimides containing amino-acid derived linkers as...

Details Bis-naphthalimides containing amino-acid derived linkers as... Bis-naphthalimides containing amino-acid derived linkers as...

C - Chemistry, Metallurgy

07

D

C07D 221/14 (2006.01) A61K 31/435 (2006.01) C07C 209/50 (2006.01) C07D 209/50 (2006.01) C07D 211/14 (2006.01)

Patent

CA 2106999

2106999 9217453 PCTABS00016 This invention relates to bis-naphthalimides, including 2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]-bis[5-nitro-1H-benz[_ de]isoquinoline-1,3(2H)-dione] and 2,2'-[1,2-ethanediylbis[imino(2-methyl-2,1-ethanediyl)]]-bis[5-nitro-1H-benz[_ de]isoquinoline-1,3(2H)-dione], processes for their preparation, pharmaceutical compositions containing them, and methods of using them to treat cancer in mammals.

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