Bis(o-carboxyphenyl)ester of a c in2-8 xx aliphatic...

A - Human Necessities – 61 – K

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A61K 8/41 (2006.01) A61K 8/43 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 1095422

Atty's. Docket IR3289 ANTIBACTERIAL ORAL COMPOSITION ABSTRACT An antibacterial oral composition effective to promote oral hygiene containing an antibacterial antiplaque agent and an additive which reduces staining of dental surfaces without substantially diminishing the antibacterial and antiplaque activity of the agent. Bis-biguanido hexanes, such as chlorhexidine and alexidine, and quaternary ammonium salts, such as benzethonium chloride and cetyl pyridinium chloride, are typical examples of antibacterial agents. The antistain additive is a bis(o-carboxyphenyl)ester of a C2-8 aliphatic dicarboxylic acid such as bis(o-carboxyphenyl)succinate.

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