Bis-quaternary pyridinium-aldoxime salts and treatment of...

Details Bis-quaternary pyridinium-aldoxime salts and treatment of... Bis-quaternary pyridinium-aldoxime salts and treatment of...

C - Chemistry, Metallurgy

07

D

C07D 213/53 (2006.01) A61K 31/4425 (2006.01) A61P 39/02 (2006.01)

Patent

CA 2718407

Bis-quaternary pyridinium-aldoxime salts are disclosed, and their associated polymorphic character, along with their methods of preparation. Such polymorphic salts may then be used for treatment of exposure to cholinesterase inhibitors, such as a phosphorous containing cholinesterase inhibitor type compound.

L'invention concerne des sels de bis-pyridinium quaternaire-aldoxime, et leur caractère polymorphe associé, conjointement avec leurs procédés de préparation. De tels sels polymorphes peuvent ensuite être utilisés pour un traitement d'exposition à des inhibiteurs de la cholinestérase, tels qu'un composé de type inhibiteur de cholinestérase à teneur en phosphore.

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