C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 317/62 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) C07C 311/01 (2006.01) C07C 311/19 (2006.01) C07C 311/29 (2006.01) C07C 311/46 (2006.01) C07C 317/14 (2006.01) C07C 323/67 (2006.01) C07D 213/56 (2006.01) C07D 235/26 (2006.01) C07D 235/32 (2006.01) C07D 277/64 (2006.01) C07D 277/82 (2006.01) C07D 295/26 (2006.01) C07D 307/79 (2006.01) C07D 319/18 (2006.01) C07D 333/34 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2210889
Bis-sulfonamido hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to retroviral protease inhibiting compounds of formula (I) or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein the variables are as defined herein.
L'invention se rapporte à des composés hydroxyéthylamino contenant des bis-sulfinamides qui sont efficaces comme inhibiteurs des protéases rétrovirales, et en particulier comme inhibiteurs de la protéase du VIH. La présente invention se rapporte à des composés de la formule (I) inhibant des protéases rétrovirales, ou à un sel pharmaceutiquement acceptable, un promédicament ou un ester de ceux-ci, dans lesquels les variables sont telles que définies dans la description.
Freskos John N.
Getman Daniel P.
Sikorski James A.
Talley John J.
G.d. Searle & Co.
G.d. Searle Llc
Sim & Mcburney
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