Bisamide inhibitors of hedgehog signaling

Details Bisamide inhibitors of hedgehog signaling Bisamide inhibitors of hedgehog signaling

C - Chemistry, Metallurgy

07

D

C07D 213/82 (2006.01) A61K 31/167 (2006.01) A61K 31/4164 (2006.01) A61K 31/4196 (2006.01) A61K 31/44 (2006.01) A61K 31/444 (2006.01) A61K 31/4453 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/5375 (2006.01) C07D 231/14 (2006.01) C07D 239/28 (2006.01) C07D 277/56 (2006.01) C07D 401/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2629814

The invention provides inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula (I), wherein ring A, ring B, R1, R2, R3, R4, R5, m and n are as defined herein.

La présente invention concerne des inhibiteurs du signal hedgehog qui sont utiles comme agents thérapeutiques pour traiter des malignités, dans lesquels les composés présentent la formule générale (I), le noyau A, le noyau B, R1, R2, R3, R4, R5, m et n étant tels que définis ici.

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