Bispecific monoclonal antibodies, their production and use

C - Chemistry – Metallurgy – 12 – P

Patent

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167/139, 195/1.1

C12P 21/08 (2006.01) A61K 39/44 (2006.01) A61K 47/48 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C07K 16/46 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2039259

TITLE: BISPECIFIC MONOCLONAL ANTIBODIES, THEIR PRODUCTION AND USE ABSTRACT Disclosed are a bispecific hybrid MoAb having specificity for both an activated platelet and a substance having thrombolytic activity, and a thrombolytic agent comprising the above bispecific MoAb and a substance having thrombolytic activity immunologically bound thereto, whereby efficient, rapid thrombolysis is possible.

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