Bispecific oligonucleotide for the treatment of cns...

A - Human Necessities – 61 – K

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Details

A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/7115 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2539727

Pharmaceutical compositions for treatment of CNS malignancies comprising a sequence of bases that is complementary to portions of both the gene encoding IGFBP-2 and the gene encoding IGFBP-5 are provided. Methods of using the pharmaceutical composition in the treatment of CNS malignancy via various modes of administration are also provided.

La présente invention concerne des compositions pharmaceutiques destinées au traitement des malignités atteignant le système nerveux central. Il s'agit d'une suite de bases qui est complémentaire de parties, non seulement du gène codant IGFBP-2, mais aussi du gène codant IGFBP-5. L'invention concerne également des procédés pour l'utilisation de la composition pharmaceutique pour le traitement des malignités atteignant le système nerveux central, en recourant à divers modes d'administration.

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