Bispecific trigger molecules recognizing lymphocyte antigen...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/46 (2006.01) A61K 35/28 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2129183

The present invention relates to novel and highly effective bispecific antibody fragments which recognize lymphocyte CD2 antigen and any variable tumor antigen. Moreover, the invention relates to two new monoclonal antibodies termed AICD2.M1 and AICD2.M2. A combination of these antibodies, whereby at least one of them is a bispecfic antibody fragment, can be used successfully in tumor therapy and diagnostics.

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