C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/38 (2006.01) A61L 24/00 (2006.01) A61L 24/06 (2006.01) A61F 2/46 (2006.01)
Patent
CA 2223450
Disclosed is a bisphosphonate bone cement for preventing periprosthetic bone loss and aseptic loosening of a joint prosthesis in patients, which cement contains a bisphosphonate bone resorption inhibitor, e.g., sodium or calcium salt of alendronate, and a pharmaceutically acceptable polymeric carrier such as polymethylmethacrylate.
L'invention se rapporte à un ciment d'os au bisphosphonate qui permet d'éviter la déperdition osseuse périprothétique et le relâchement aseptique d'une prothèse articulaire chez les patients. Ledit ciment contient un inhibiteur de résorption osseuse au bisphosphonate (par exemple du sel de sodium ou du sel de calcium d'alendronate), et un vecteur polymère pharmaceutiquement acceptable tel que le polyméthacrylate de méthyle.
Athanasou Nick
Simpson Hamish
Yates Ashley J.
Athanasou Nick
Merck & Co. Inc.
Simpson Hamish
Swabey Ogilvy Renault
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