A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/663 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2502284
A method for the treatment of atherosclerosis, in particular atherosclerotic/valve calcification and plaque rupture/stroke, in a patient in need of such treatment, e.g. a patient with aterial or valve calcification, which comprises administering an effective amount of a bisphosphonate, e.g. zoledronic acid or salts or hydrates thereof, to the patient. Especially the invention relates to the local administration the bisphosphonate and to a device, e.g. stent adapted for such local administration.
L'invention concerne une méthode permettant de traiter l'athérosclérose, notamment la calcification athérosclérotique/valvulaire et la rupture de plaque athérosclérotique/l'accident cérébral vasculaire, chez un patient requérant un traitement de ce type, par ex. un patient souffrant de calcification artérielle ou valvulaire. Cette méthode comprend l'administration au patient concerné, d'une quantité efficace de bisphosphonate, c.-à-d. d'acide zolédronique ou de sels ou d'hydrates dudit acide. L'invention concerne notamment l'administration locale de bisphosphonate, ainsi qu'un dispositif, c.-à-d. un tuteur intravasculaire adapté pour un tel mode d'administration locale.
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
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