Bisphosphonic acid derivatives, their production and use

C - Chemistry – Metallurgy – 07 – F

Patent

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C07F 9/38 (2006.01) A61K 31/66 (2006.01) C07F 9/40 (2006.01) C07F 9/547 (2006.01) C07F 9/58 (2006.01) C07F 9/6506 (2006.01) C07F 9/6512 (2006.01) C07F 9/6524 (2006.01) C07F 9/6539 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2045293

Abstract of the disclosure: BISPHOSPHONIC ACID DERIVATIVES, THEIR PRODUCTION AND USE A bisphosphonic acid derivative of the general formula (I): Image (I) wherein A is an optionally substituted cyclic group; R1 is hydrogen atom or a lower alkanoyl group; R2, R3, R4 and R5 are the same or different and are hydrogen atom or a lower alkyl group; m is 0, 1 or 2; and n is an integer from 2 to 10, or a salt thereof is disclosed. A process for its production and a bone resorption inhibitor containing the compound of the general formula (I) or a salt thereof are also disclosed.

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