Bispiperidines as antithrombotic agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 211/34 (2006.01) A61K 31/445 (2006.01) C07D 211/60 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2337776

The invention concerns compounds of formula (I) wherein: R1, R2, R3, Z1, Z2 are as defined in Claim 1. Said compounds inhibit the fixing of fibrinogen on Gp IIb/IIIa platelet receptors and are useful in therapy as antithrombotic agents.

La présente invention concerne des composés de formule (I) dans laquelle R¿1?, R¿2?, R¿3?, Z¿1?, Z¿2? et A sont tels que définis à la revendication 1. Ces composés sont des inhibiteurs de la fixation du fibrinogène sur les récepteurs plaquettaires Gp IIb/IIIa et sont utilisables en thérapeutique comme antithrombotiques.

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