Bisplatinum complexes as chemotherapeutic agents

C - Chemistry – Metallurgy – 07 – F

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C07F 15/00 (2006.01) A61K 31/28 (2006.01) A61K 31/555 (2006.01)

Patent

CA 1340892

A bis-platinum complex having the structure: Image wherein X and Y are the same or different ligands and are halide, sulphate, phosphate, nitrate, carboxylate, substituted carboxylate or dicarboxylate. B and C are the same or different and are primary or secondary amines, or pyridine type nitrogens. A is a diamine or polyamine wherein the primary amine N atoms are coordinated to the Pt atom such that platinum is present as Pt2+. The complexes are useful in the inhibition of tumors.

542812

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