Bk beta subunits of slo family potassium channels

Details Bk beta subunits of slo family potassium channels Bk beta subunits of slo family potassium channels

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07K 1/00 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12P 19/34 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2363626

The invention provides isolated nucleic acid and amino acid sequences of BK beta 2, BK beta 3, and BK beta 4, antibodies to the BKbeta subunits, methods of detecting the BK beta subunits, methods of screening for modulators of Slo potassium channels comprising BK beta subunits, and kits for screening for activators and inhibitors of the Slo family potassium channels comprising BK beta subunits.

La présente invention concerne des séquences d'acides nucléiques et d'acides aminés isolées de BK bêta 2, BK bêta 3, et BK bêta 4, des anticorps contre les sous-unités de BK bêta, des procédés de détection des sous-unités de BK bêta, des procédés de criblage des modulateurs de canaux potassiques Slo comportant des sous-unités de BK bêta, et des kits de criblage d'activateurs et d'inhibiteurs des canaux potassiques de la famille Slo comportant des sous-unités BK bêta.

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