Blister package for topiramate tablets

A - Human Necessities – 61 – J

Patent

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A61J 1/03 (2006.01) B65D 75/34 (2006.01)

Patent

CA 2409975

The present invention provides a blister package for topiramate tablets comprising a pan sheet having preformed cavities containing topiramate tablets dried to a free water content of between about 0.4 % to about 1.4 % and a cover sheet sealed to the pan sheet. The present invention further provides a process for blister packaging dried topiramate tablets into a blister package with improved shelf-life and stability performance.

La présente invention concerne un emballage coque destiné à des comprimés de topiramate, lequel consiste en une feuille à dragées dans laquelle on a perforé des cavités renfermant des comprimés de topiramate qui sont desséchés jusqu'à l'obtention de comprimés dont la teneur en eau libre est comprise entre environ 0,4 % et environ 1,4 %, ainsi qu'une feuille couvrante fixée de manière hermétique à la feuille à dragées. La présente invention concerne également un procédé permettant d'emballer des comprimés de topiramate desséchés dans un emballage coque présentant une durée de conservation et une performance de stabilité améliorées.

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