Block polymer having functional groups on its both ends

C - Chemistry – Metallurgy – 08 – G

Patent

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Details

C08G 65/32 (2006.01) A61K 47/34 (2006.01) A61K 47/48 (2006.01) C08G 63/66 (2006.01) C08G 63/664 (2006.01) C08G 63/676 (2006.01) C08G 63/91 (2006.01) C08G 65/26 (2006.01) C08G 65/329 (2006.01) C08G 85/00 (2006.01) C08L 71/02 (2006.01) A61K 9/107 (2006.01) A61K 9/51 (2006.01)

Patent

CA 2229068

A block polymer having functional groups at both ends of its molecule and comprising hydrophilic/hydrophobic segments. As the functional groups at both ends, the polymer carries amino, carboxy or mercapto at the .alpha.-end and hydroxy, carboxy, aldehyde, vinyl, etc. at the .omega.-end. The hydrophilic segment comprises polyoxyethylene while the hydrophobic segment is one derived from lactide, lactone or (meth)acrylate. This block polymer forms a polymeric micelle and is applicable to biocompatible materials, etc.

Polymère séquencé pourvu de groupes fonctionnels aux deux extrémités de sa molécule et comprenant des segments hydrophiles/hydrophobes. Comme groupes fonctionnels à ses deux extrémités, le polymère porte amino, carboxy ou mercapto à l'extrémité .alpha. et hydroxy, carboxy, aldéhyde, vinyle, etc. à l'extrémité .omega.. Le segment hydrophile comprend du polyoxyéthylène, alors que le segment hydrophobe est obtenu à partir de lactide, lactone ou (méth)acrylate. Ce polymère séquencé forme une micelle polymère et s'applique à des matériaux polymères, etc.

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