Blockade of t cell migration into epithelial gvhd target...

Details Blockade of t cell migration into epithelial gvhd target... Blockade of t cell migration into epithelial gvhd target...

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) A61P 37/06 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2428721

Antagonists of T cell migration are used to reduce GVHD in recipients of hemaopoietic cell grafts. The administration of antagonists of T cell migration can be used in combination with conventional methods of bone marrow transplantation and in combination with the administration of donor leukocytes.

L'invention concerne l'utilisation d'antagonistes de la migration des lymphocytes T pour réduire l'incidence de la GvH chez les receveurs de greffes de cellules hématopoïétiques. On peut combiner l'administration de ces antagonistes de la migration des lymphocytes T à des méthodes de greffe de moelle osseuse classiques et à l'administration de leucocytes du donneur.

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