Blocking the metastasis of cancer cells and the uses of new...

A - Human Necessities – 61 – K

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A61K 31/704 (2006.01) A61P 33/00 (2006.01) C07J 53/00 (2006.01) C07J 63/00 (2006.01)

Patent

CA 2715501

Methods for utilizing the anticancer properties of terpenoid saponin compounds so as to modulate adhesion proteins, inhibit angiogenesis in tumors, modulate gene expression, modulate angiopoietin, enhance an immune response, provide adjuvant activities, provide vaccine activities, or inhibit the metastasis of cancer cells when contacting a subject with the compounds, wherein the cancers compose breast cancer, leukocyte cancer, liver cancer, ovarian cancer, bladder cancer, prostate cancer, skin cancer, bone cancer, brain cancer, leukemia cancer, lung cancer, colon cancer, CNS cancer, melanoma cancer, renal cancer, cervix cancer, esophagus cancer, testis cancer, spleen cancer, kidney cancer, lymph cancer, pancreas cancer, stomach cancer and thyroid cancer Methods, processes, compounds and compositions for antiparasitic applications which include inhibiting leish-maniases, amoebiasis, trypanosomiasis, toxoplasmosis or malaria

La présente invention concerne des procédés permettant d'utiliser des propriétés anticancéreuses de composés saponine terponoïde afin de moduler l'expression génique, moduler l'angiopoiétine, renforcer la réponse immune et fournir des activités adjuvantes, des activités de vaccin ou inhiber les métastases de cellules cancéreuses lorsqu'un patient est en contact avec ces composés. Les cancers comprennent le cancer du sein, le cancer des leucocytes, le cancer du foie, le cancer ovarien, le cancer de la vessie, le cancer de la prostate, le cancer de la peau, le cancer des os, le cancer du cerveau, la leucémie, le cancer du poumon, le cancer du côlon, le cancer du SNC, le mélanome, le cancer rénal, le cancer du col de lutérus, le cancer de lsophage, le cancer des testicules, le cancer de la rate, le cancer du rein, le cancer lymphatique, le cancer du pancréas, le cancer de lestomac et le cancer de la thyroïde. La présente invention concerne des procédés, des processus, des composés et des compositions pour des applications antiparasitaires, qui comprennent l'inhibition des leishmanioses, des amibiases, des trypanosomiases, de la toxoplasmose ou du paludisme.

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