Blood cholesterol level reducing agent and method

Details Blood cholesterol level reducing agent and method Blood cholesterol level reducing agent and method

A - Human Necessities

61

K

167/127

A61K 33/26 (2006.01) A61K 9/00 (2006.01) A61K 9/50 (2006.01) A61K 31/74 (2006.01) A61K 31/785 (2006.01)

Patent

CA 1177752

ABSTRACT OF THE DISCLOSURE An agent for reducing the cholesterol level in the blood of a warm blooded animal comprises a plurality of vesicles pre- pared from a non-toxic, non-biodegradable, semi-permeable material, and a quantity of a bile acid sequestrant provided in liquid form. The liquid sequestrant is disposed within the vesicles in an amount by volume of up to ninety percent of the available internal volume of the vesicle. The vesi- cles selectively permit the ingress of bile acids, and may preferably possess an electrical charge on their outer surface to assist the passage of the bile acids therethrough. The present invention includes a method for reducing the cholesterol level in the blood, comprising administering the the reducing agent. Oral administration is preferred, and, in one embodiment, the reducing agent comprising a plurality of the vesicles may be contained within a capsule or the like.

381508

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