Blood-coagulation factor xiia .beta. monoclonal antibody and...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) C07K 16/40 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2045475

A monoclonal antibody which binds to Factor .beta.XII and which shows substantially no binding to Factor XII. This antibody may be used in immunoassays to measure Factor .beta.XIIa levels in blood, for example for studies of blood coagulation systems and of thrombotic disorders.

Un anticorps monoclonal se lie au facteur betaXII et ne se lie guère au facteur XII. Cet anticorps peut être utilisé dans des essais immunitaires pour mesurer le niveau de facteur betaXIIa dans le sang, par exemple lors d'études de systèmes de coagulation sanguine et de troubles thrombotiques.

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