Blood-coagulation-promoting products and method of preparing...

Details Blood-coagulation-promoting products and method of preparing... Blood-coagulation-promoting products and method of preparing...

A - Human Necessities

61

K

195/39.1

A61K 35/16 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1170182

ABSTRACT OF THE DISCLOSURE Blood-coagulation-promoting products substantially free of thrombin are prepared from human blood plasma by contacting a human blood plasma fraction containing coagulation Factors II, VII, IX and X with an anion exchanger to adsorb the coagulation Factors, which are subsequently eluted from the anion exchanger. The eluate is treated to generate a substance having Factor VIII Inhibitor Bypassing Activity and being substantially free of thrombin, and activated Factor X.

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