Blood-compatible polymer surfaces

Details Blood-compatible polymer surfaces Blood-compatible polymer surfaces

G - Physics

01

N

G01N 33/545 (2006.01) A61L 27/28 (2006.01) A61L 27/54 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/08 (2006.01) A61L 31/16 (2006.01) A61L 33/00 (2006.01) A61L 33/12 (2006.01) C12N 11/08 (2006.01) G01N 33/555 (2006.01)

Patent

CA 2392080

The invention relates to a blood-compatible surface comprising a polymer surface and a plurality of conjugates made of linkers and active agents immobilised thereon. The polymer surface contains similar or different structural units that carry carbonyl groups. The linkers contain a structural element that is able to form a hydrogen bridge bond. A polyorganosiloxane acting as the active agent is linked to the linkers.

L'invention concerne des surfaces hémocompatibles, constituées d'une surface de polymère sur lequel est immobilisée une pluralité de conjugués lieur-principe actif, ladite surface de polymère présentant des unités structurales identiques ou différentes, qui portent des groupes carbonyle, les lieurs contenant un élément structural qui peut former une liaison en pont hydrogène, et un polyorganosiloxane étant rattaché, comme principe actif, aux lieurs.

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