Blood levels of cck peptides relative to panic disorder...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61K 31/135 (2006.01) A61K 31/505 (2006.01) G01N 30/64 (2006.01) G01N 30/88 (2006.01) G01N 33/48 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2140241

A method of treating a patient having a panic disorder, the patient having an elevated CCK peptide plasma level, by lower- ing the plasma CCK peptide level of the patient. A further method provides a diagnosis of panic disorder in a patient by detect- ing if that patient's plasma contains elevated CCK peptide levels. A further method determines the efficacy of the drug for the treatment of panic disorder by detecting the ability of the drug to lower elevated CCK peptide levels in a model for panic disor- der. Additionally, a method of dosing a patient having elevated CCK peptide levels with an antipanic disorder drug is character- ized by administering the drug to a patient and monitoring the lowering of the elevated plasma CCK peptide levels of the patient.

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