Blood platelet induction method

Details Blood platelet induction method Blood platelet induction method

C - Chemistry, Metallurgy

12

N

C12N 5/078 (2010.01) C12M 3/00 (2006.01) C12M 3/04 (2006.01)

Patent

CA 2724043

Disclosed is a new induction method to effectively produce blood platelets from platelet precursor cells typified by hematopoietic/precursor cells, wherein said blood platelet induction method causes platelet precursor cells to differentiate into blood platelets by culturing platelet precursor cells in a culture medium into which is immersed a special composite membrane comprising a porous thin film that is laminated onto at least one surface of a porous support membrane.

La présente invention concerne un nouveau procédé d'induction permettant de produire efficacement des plaquettes sanguines à partir de cellules précurseurs des plaquettes dont le type est établi par les cellules hématopoïétiques ou les cellules précurseurs. En l'occurrence, pour obtenir des plaquettes sanguines par différenciation des cellules précurseurs des plaquettes, le procédé d'induction consiste à mettre en culture des cellules précurseurs de plaquettes dans un milieu de culture dans lequel est plongé une membrane composite spéciale comprenant une couche mince poreuse stratifiée sur au moins une face d'une membrane support poreuse.

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