Blood substitute containing modified hemoglobin

A - Human Necessities – 61 – K

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A61K 35/18 (2006.01) A61K 31/74 (2006.01) C07K 14/805 (2006.01) C08G 65/32 (2006.01) C08L 71/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1146858

ABSTRACT OF THE DISCLOSURE A novel modified hemoglobin comprises hemoglobin coupled with a polyalkylene glycol or its derivative, and is useful as a blood substitute; the oxygen-carrying capa- city of this hemoglobin is nearly equal to that of native hemoglobin, and the residence time in the circulation is satisfactorily long.

356067

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