Bluetongue virus vaccine and immunogenic compositions,...

A - Human Necessities – 61 – K

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A61K 39/15 (2006.01)

Patent

CA 2706514

Provided are immunogenic and vaccine compositions and methods for their preparation and use, which compositions are effective in protecting against, minimizing the severity of, preventing, and/or ameliorating infection of ruminants with Bluetongue virus. Administration to an animal of at least one dose of an adjuvanted and twice inactivated Bluetongue virus com- position as disclosed herein is effective in providing immunity to the animal and protection from infection with Bluetongue virus, thereby reducing the severity of and/or preventing disease caused by one or more strains or serotypes of Bluetongue virus.

L'invention concerne des compositions immunogènes et de vaccin et leurs procédés de préparation et d'utilisation, lesdites compositions étant efficaces pour protéger contre, minimiser la gravité de, prévenir et/ou améliorer l'infection des ruminants par le virus de la fièvre catarrhale du mouton. L'administration à un animal d'au moins une dose d'une composition de virus de la fièvre catarrhale du mouton avec adjuvant et inactivée à deux reprises, telle que décrite dans le présent document permet de fournir de manière efficace une immunité à l'animal et de le protéger d'une infection par le virus de la fièvre catarrhale du mouton, réduisant ainsi la gravité de et/ou prévenant la maladie causée par une ou plusieurs souches ou sérotypes du virus de la fièvre catarrhale du mouton.

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